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A human monoclonal antibody specific to placental alkaline phosphatase, a marker of ovarian cancer
Placental alkaline phosphatase (PLAP) is a promising ovarian cancer biomarker. Here, we describe the isolation, affinity-maturation and characterization of two fully human monoclonal antibodies (termed B10 and D9) able to bind to human PLAP with a dissociation constant (K(d)) of 10 and 30 nM, respec...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929458/ https://ncbi.nlm.nih.gov/pubmed/24247025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27230 |
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