Stabilized Interleukin-6 receptor binding RNA aptamers

Interleukin-6 (IL-6) is a multifunctional cytokine that is involved in the progression of various inflammatory diseases, such as rheumatoid arthritis and certain cancers; for example, multiple myeloma or hepatocellular carcinoma. To interfere with IL-6-dependent diseases, targeting IL-6 receptor (IL...

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Bibliographic Details
Main Authors: Meyer, Cindy, Berg, Katharina, Eydeler-Haeder, Katja, Lorenzen, Inken, Grötzinger, Joachim, Rose-John, Stefan, Hahn, Ulrich
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929425/
https://ncbi.nlm.nih.gov/pubmed/24440854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.27447
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