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Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptors
The RIG-I-like receptors (RLRs)—RIG-I, MDA5, and LGP2—detect intracellular pathogenic RNA and elicit an antiviral immune response during viral infection. The protein architecture of the RLR family consists of multiple functional domains, including N-terminal Caspase Activation and Recruitment Domain...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2014
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929420/ https://ncbi.nlm.nih.gov/pubmed/24457940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.27717 |
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