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Single continuous lumen formation in the zebrafish gut is mediated by smoothened-dependent tissue remodeling

The formation of a single lumen during tubulogenesis is crucial for the development and function of many organs. Although 3D cell culture models have identified molecular mechanisms controlling lumen formation in vitro, their function during vertebrate organogenesis is poorly understood. Using light...

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Autors principals: Alvers, Ashley L., Ryan, Sean, Scherz, Paul J., Huisken, Jan, Bagnat, Michel
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929411/
https://ncbi.nlm.nih.gov/pubmed/24504339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.100313
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