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Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells

Mammary ducts are elongated during development by stratified epithelial structures, known as terminal end buds (TEBs). TEBs exhibit reduced apicobasal polarity and extensive proliferation. A major unanswered question concerns the mechanism by which the simple ductal epithelium stratifies during TEB...

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Bibliografiska uppgifter
Huvudupphovsmän: Huebner, Robert J., Lechler, Terry, Ewald, Andrew J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Company of Biologists 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929409/
https://ncbi.nlm.nih.gov/pubmed/24550116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.103333
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