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Earmuff restricts progenitor cell potential by attenuating the competence to respond to self-renewal factors

Despite expressing stem cell self-renewal factors, intermediate progenitor cells possess restricted developmental potential, which allows them to give rise exclusively to differentiated progeny rather than stem cell progeny. Failure to restrict the developmental potential can allow intermediate prog...

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Podrobná bibliografie
Hlavní autoři: Janssens, Derek H., Komori, Hideyuki, Grbac, Daniel, Chen, Keng, Koe, Chwee Tat, Wang, Hongyan, Lee, Cheng-Yu
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929404/
https://ncbi.nlm.nih.gov/pubmed/24550111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.106534
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