Benzimidazoisoquinolines: A New Class of Rapidly Metabolized Aryl Hydrocarbon Receptor (AhR) Ligands that Induce AhR-Dependent Tregs and Prevent Murine Graft-Versus-Host Disease

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that plays multiple roles in regulation of immune and inflammatory responses. The ability of certain AhR ligands to induce regulatory T cells (Tregs) has generated interest in developing AhR ligands for therapeutic treatm...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Punj, Sumit, Kopparapu, Prasad, Jang, Hyo Sang, Phillips, Jessica L., Pennington, Jamie, Rohlman, Diana, O’Donnell, Edmond, Iversen, Patrick L., Kolluri, Siva Kumar, Kerkvliet, Nancy I.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929365/
https://ncbi.nlm.nih.gov/pubmed/24586378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088726
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
Cargando...

Títulos similares