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Temperature-sensitive mutants of mouse hepatitis virus produce a high incidence of demyelination.

Mutagenesis of mouse hepatitis virus with 5-azacytidine or 5-fluorouracil yielded several temperature-sensitive mutants. Mutants have been isolated that dramatically enhance the production of demyelinating disease over that previously noted with the wild-type virus. This reproducible model should no...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Haspel, M V, Lampert, P W, Oldstone, M B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1978
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC392925/
https://ncbi.nlm.nih.gov/pubmed/279022
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