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Temperature-sensitive mutants of mouse hepatitis virus strain A59: Isolation, characterization and neuropathogenic properties

Twenty 5-fluorouracil-induced temperature-sensitive (ts) mutants of mouse hepatitis virus strain A59 were isolated from 1284 virus clones. Mutants were preselected on the basis of their inability to induce syncytia in infected cells at the restrictive temperature (40°) vs the permissive temperature...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Virology
Autori principali: Koolen, Marck J.M., Osterhaus, Albert D.M.E., Van Steenis, Gijsbert, Horzinek, Marian C., van der Zeijst, Bernard A.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Published by Elsevier Inc. 1983
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126919/
https://ncbi.nlm.nih.gov/pubmed/6301146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0042-6822(83)90211-8
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