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Gaucher disease: isolation and comparison of normal and mutant glucocerebrosidase from human spleen tissue.

Glucocerebrosidase was purified 26,000-fold from spleens from normal humans and from patients with Gaucher disease (Gaucher spleens). The specific activities of the purified normal and mutant enzymes with glucocerebroside as substrate were 8.5 X 10(5) and 5.4 X 10(4) nmol/mg of protein per hr, respe...

詳細記述

保存先:
書誌詳細
主要な著者: Pentchev, P G, Brady, R O, Blair, H E, Britton, D E, Sorrell, S H
フォーマット: Artigo
言語:Inglês
出版事項: 1978
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC392911/
https://ncbi.nlm.nih.gov/pubmed/29293
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