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SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplification caused by loss of polycystin-1

The mechanisms underlying many of the human disease phenotypes associated with ciliary dysfunction and abnormal centrosome amplification have yet to be fully elucidated. Here, we present for the first time that SIRT2, a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase, regulates cilioge...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhou, Xia, Fan, Lucy X., Li, Keguo, Ramchandran, Ramani, Calvet, James P., Li, Xiaogang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929098/
https://ncbi.nlm.nih.gov/pubmed/24203696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt556
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