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Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models

Neuronal mitochondrial morphology abnormalities occur in models of familial amyotrophic lateral sclerosis (ALS) associated with SOD1 and TDP43 mutations. These abnormalities have been linked to mitochondrial axonal transport defects, but the temporal and spatial relationship between mitochondrial mo...

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Библиографические подробности
Главные авторы: Magrané, Jordi, Cortez, Czrina, Gan, Wen-Biao, Manfredi, Giovanni
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929084/
https://ncbi.nlm.nih.gov/pubmed/24154542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt528
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