The anti-atherogenic cytokine interleukin-33 inhibits the expression of a disintegrin and metalloproteinase with thrombospondin motifs-1, -4 and -5 in human macrophages: Requirement of extracellular signal-regulated kinase, c-Jun N-terminal kinase and phosphoinositide 3-kinase signaling pathways()

Atherosclerosis is an inflammatory disorder of the vasculature regulated by cytokines. Amongst the cytokines, IL-33 attenuates the development of atherosclerosis in mouse model systems via several mechanisms, including inhibition of macrophage foam cell formation and promotion of a Th1 to Th2 shift....

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Detalhes bibliográficos
Main Authors: Ashlin, Tim G., Buckley, Melanie L., Salter, Rebecca C., Johnson, Jason L., Kwan, Alvin P.L., Ramji, Dipak P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928996/
https://ncbi.nlm.nih.gov/pubmed/24275094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2013.11.008
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