On the fate of primordial germ cells injected into early mouse embryos()

Primordial germ cells (PGCs) are the founder cells of the germline. Via gametogenesis and fertilisation this lineage generates a new embryo in the next generation. PGCs are also the cell of origin of multilineage teratocarcinomas. In vitro, mouse PGCs can give rise to embryonic germ (EG) cells – plu...

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Main Authors: Leitch, Harry G., Okamura, Daiji, Durcova-Hills, Gabriela, Stewart, Colin L., Gardner, Richard L., Matsui, Yasuhisa, Papaioannou, Virginia E.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
Fag:
Perspective
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928994/
https://ncbi.nlm.nih.gov/pubmed/24269765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.11.014
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