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Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.

Infection of cells with picornaviruses, such as poliovirus and encephalomyocarditis virus (EMCV), causes a shutoff of host protein synthesis. The molecular mechanism of the shutoff has been partly elucidated for poliovirus but not for EMCV. Translation initiation in eukaryotes is facilitated by the...

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Библиографические подробности
Опубликовано в::Proc Natl Acad Sci U S A
Главные авторы: Gingras, A C, Svitkin, Y, Belsham, G J, Pause, A, Sonenberg, N
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1996
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Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39289/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.11.5578
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