Rapamycin and Wortmannin Enhance Replication of a Defective Encephalomyocarditis Virus

Inhibitors of the phosphatidylinositol 3-kinase (PI3 kinase)–FKBP-rapamycin-associated protein (FRAP) pathway, such as rapamycin and wortmannin, induce dephosphorylation and activation of the suppressor of cap-dependent translation, 4E-BP1. Encephalomyocarditis virus (EMCV) infection leads to activa...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Svitkin, Yuri V., Hahn, Harry, Gingras, Anne-Claude, Palmenberg, Ann C., Sonenberg, Nahum
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 1998
Aiheet:
Virus-Cell Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC110383/
https://ncbi.nlm.nih.gov/pubmed/9621041
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