Rapamycin and Wortmannin Enhance Replication of a Defective Encephalomyocarditis Virus

Inhibitors of the phosphatidylinositol 3-kinase (PI3 kinase)–FKBP-rapamycin-associated protein (FRAP) pathway, such as rapamycin and wortmannin, induce dephosphorylation and activation of the suppressor of cap-dependent translation, 4E-BP1. Encephalomyocarditis virus (EMCV) infection leads to activa...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Svitkin, Yuri V., Hahn, Harry, Gingras, Anne-Claude, Palmenberg, Ann C., Sonenberg, Nahum
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110383/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9621041/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.7.5811-5819.1998
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