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Insulin downregulates the expression of the Ca(2+)-activated nonselective cation channel TRPM5 in pancreatic islets from leptin-deficient mouse models
We recently proposed that the transient receptor potential melastatin 5 (TRPM5) cation channel contributes to glucose-induced electrical activity of the β cell and positively influences glucose-induced insulin release and glucose homeostasis. In this study, we investigated Trpm5 expression and funct...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Berlin Heidelberg
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3928505/ https://ncbi.nlm.nih.gov/pubmed/24221356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-013-1389-7 |
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