Extracellular Zinc Competitively Inhibits Manganese Uptake and Compromises Oxidative Stress Management in Streptococcus pneumoniae

Streptococcus pneumoniae requires manganese for colonization of the human host, but the underlying molecular basis for this requirement has not been elucidated. Recently, it was shown that zinc could compromise manganese uptake and that zinc levels increased during infection by S. pneumoniae in all...

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Detalhes bibliográficos
Main Authors: Eijkelkamp, Bart A., Morey, Jacqueline R., Ween, Miranda P., Ong, Cheryl-lynn Y., McEwan, Alastair G., Paton, James C., McDevitt, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928430/
https://ncbi.nlm.nih.gov/pubmed/24558498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089427
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