Glibenclamide Decreases ATP-Induced Intracellular Calcium Transient Elevation via Inhibiting Reactive Oxygen Species and Mitochondrial Activity in Macrophages

Increasing evidence has revealed that glibenclamide has a wide range of anti-inflammatory effects. However, it is unclear whether glibenclamide can affect the resting and adenosine triphosphate (ATP)-induced intracellular calcium ([Ca(2+)](i)) handling in Raw 264.7 macrophages. In the present study,...

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Main Authors: Li, Duo-ling, Ma, Zhi-yong, Fu, Zhi-jie, Ling, Ming-ying, Yan, Chuan-zhu, Zhang, Yun
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928368/
https://ncbi.nlm.nih.gov/pubmed/24558474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089083
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