Epigenetic regulation of miR-21 in colorectal cancer: ITGB4 as a novel miR-21 target and a three-gene network (miR-21-ITGΒ4-PDCD4) as predictor of metastatic tumor potential

Previous studies have uncovered several transcription factors that determine biological alterations in tumor cells to execute the invasion-metastasis cascade, including the epithelial-mesenchymal transition (EMT). We sought to investigate the role of miR-21 in colorectal cancer regulation. For this...

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Detalhes bibliográficos
Main Authors: Ferraro, Angelo, Kontos, Christos K, Boni, Themis, Bantounas, Ioannis, Siakouli, Dimitra, Kosmidou, Vivian, Vlassi, Margarita, Spyridakis, Yannis, Tsipras, Iraklis, Zografos, George, Pintzas, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928175/
https://ncbi.nlm.nih.gov/pubmed/24149370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.26842
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