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Irinotecan disrupts tight junction proteins within the gut: Implications for chemotherapy-induced gut toxicity

Chemotherapy for cancer causes significant gut toxicity, leading to severe clinical manifestations and an increased economic burden. Despite much research, many of the underlying mechanisms remain poorly understood hindering effective treatment options. Recently there has been renewed interest in th...

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Detalhes bibliográficos
Main Authors: Wardill, Hannah R, Bowen, Joanne M, Al-Dasooqi, Noor, Sultani, Masooma, Bateman, Emma, Stansborough, Romany, Shirren, Joseph, Gibson, Rachel J
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928140/
https://ncbi.nlm.nih.gov/pubmed/24316664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27222
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