Insulin resistance due to a defect distal to the insulin receptor: Demonstration in a patient with leprechaunism
We have studied a 2-year-old girl with acanthosis nigricans, glucose intolerance, marked hyperinsulinemia, and somatic features characteristic of the leprechaunism syndrome. Circulating plasma insulin levels were increased up to 50-fold and the patient showed a blunted hypoglycemic response to an in...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1978
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392799/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/277948/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.7.3469 |
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