ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis

The transmembrane metalloprotease-disintegrin ADAM8 mediates cell adhesion and shedding of ligands, receptors and extracellular matrix components. Here, we report that ADAM8 is abundantly expressed in breast tumors and derived metastases compared to normal tissue, especially in triple-negative breas...

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Bibliografiska uppgifter
Huvudupphovsmän: Romagnoli, Mathilde, Mineva, Nora D, Polmear, Michael, Conrad, Catharina, Srinivasan, Srimathi, Loussouarn, Delphine, Barillé-Nion, Sophie, Georgakoudi, Irene, Dagg, Áine, McDermott, Enda W, Duffy, Michael J, McGowan, Patricia M, Schlomann, Uwe, Parsons, Maddy, Bartsch, Jörg W, Sonenshein, Gail E
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927960/
https://ncbi.nlm.nih.gov/pubmed/24375628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201303373
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