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Preparation and Activities of Macromolecule Conjugates of the CCR5 Antagonist Maraviroc

[Image: see text] CCR5 antagonists are among the most advanced approaches in HIV therapy and may also be relevant to treatment of graft-versus-host disease and Staphylococcus aureus infection. To expand the potential of the only approved CCR5 antagonist, Maraviroc, we studied derivatives that would...

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Autors principals: Asano, Shigehiro, Gavrilyuk, Julia, Burton, Dennis R., Barbas, Carlos F.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2013
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927940/
https://ncbi.nlm.nih.gov/pubmed/24563723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400370w
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