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Potential for intranasal drug delivery to alter cerebrospinal fluid outflow via the nasal turbinate lymphatics

BACKGROUND: Cerebrospinal fluid absorption (CSF) at the cribriform plate is mediated by direct extracranial connections to the lymphatic system. Given the accessibility of these pharmacologically responsive vessels we hypothesized that the rate of CSF outflow can be modulated via the intranasal deli...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, Harold, Moore, Sara A, Johnston, Miles G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927830/
https://ncbi.nlm.nih.gov/pubmed/24528926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-11-4
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