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Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice

Cerebrospinal fluid (CSF) has been commonly accepted to drain through arachnoid projections from the subarachnoid space to the dural venous sinuses. However, a lymphatic component to CSF outflow has long been known. Here, we utilize lymphatic-reporter mice and high-resolution stereomicroscopy to cha...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ma, Qiaoli, Ineichen, Benjamin V., Detmar, Michael, Proulx, Steven T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681558/
https://ncbi.nlm.nih.gov/pubmed/29127332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01484-6
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