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Virulence of infecting Helicobacter pyloristrains and intensity of mononuclear cell infiltration are associated with levels of DNA hypermethylation in gastric mucosae

DNA methylation changes are known to occur in gastric cancers and in premalignant lesions of the gastric mucosae. In order to examine variables associated with methylation levels, we quantitatively evaluated DNA methylation in tumors, non-tumor gastric mucosae, and in gastric biopsies at promoters o...

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Bibliografiske detaljer
Main Authors: Schneider, Barbara G, Piazuelo, M Blanca, Sicinschi, Liviu A, Mera, Robertino, Peng, Dun-Fa, Roa, Juan Carlos, Romero-Gallo, Judith, Delgado, Alberto G, de Sablet, Thibaut, Bravo, Luis E, Wilson, Keith T, El-Rifai, Wael, Peek Jr, Richard M, Correa, Pelayo
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927747/
https://ncbi.nlm.nih.gov/pubmed/24128875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.26072
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