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Virulence of infecting Helicobacter pyloristrains and intensity of mononuclear cell infiltration are associated with levels of DNA hypermethylation in gastric mucosae

DNA methylation changes are known to occur in gastric cancers and in premalignant lesions of the gastric mucosae. In order to examine variables associated with methylation levels, we quantitatively evaluated DNA methylation in tumors, non-tumor gastric mucosae, and in gastric biopsies at promoters o...

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Detalhes bibliográficos
Main Authors: Schneider, Barbara G, Piazuelo, M Blanca, Sicinschi, Liviu A, Mera, Robertino, Peng, Dun-Fa, Roa, Juan Carlos, Romero-Gallo, Judith, Delgado, Alberto G, de Sablet, Thibaut, Bravo, Luis E, Wilson, Keith T, El-Rifai, Wael, Peek Jr, Richard M, Correa, Pelayo
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927747/
https://ncbi.nlm.nih.gov/pubmed/24128875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.26072
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