HO-1 Induction by CO-RM2 Attenuates TNF-α-Induced Cytosolic Phospholipase A(2) Expression via Inhibition of PKCα-Dependent NADPH Oxidase/ROS and NF-κB

Rheumatoid arthritis (RA) is characterized by chronic inflammatory infiltration of the synovium and elevation of proinflammatory cytokines. Cytosolic phospholipase A(2) (cPLA(2)) is involved in the development of inflammatory diseases. Heme oxygenase-1 (HO-1) has been shown to possess anti-inflammat...

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Detalhes bibliográficos
Main Authors: Chi, Pei-Ling, Liu, Chun-Ju, Lee, I-Ta, Chen, Yu-Wen, Hsiao, Li-Der, Yang, Chuen-Mao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927740/
https://ncbi.nlm.nih.gov/pubmed/24616552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/279171
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