Role of nucleotides in tubulin polymerization: effect of guanosine 5'-methylene diphosphonate.
Incubation of purified rat brain tubulin with guanosine 5'-methylene diphosphonate [GMP(CH2)P] (1 mM), a GDP analog resistant to hydrolysis, results in the polymerization of 20-30% of the total tubulin present. Analogous incubations with GDP (1 mM) do not result in tubulin polymerization. Polymeriza...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1978
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392737/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/277919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.7.3178 |
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