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A new method to detect contaminants in heparin using radical depolymerization and liquid chromatography-mass spectrometry
Heparin is a critically important anticoagulant drug that was contaminated with a persulfonated polysaccharide in 2008, resulting in a number of severe adverse reactions, some leading to death. Controversy remains as to the precise composition of the 2008 contaminant and new information suggests tha...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3927312/ https://ncbi.nlm.nih.gov/pubmed/24364596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac403625a |
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