A small-molecule inducer of PDX1 expression identified by high-throughput screening

Pancreatic and duodenal homeobox 1 (PDX1), a member of the homedomain-containing transcription factor family, is a key transcription factor important for both pancreas development and mature beta-cell function. The ectopic overexpression of Pdx1, Neurog3, and MafA in mice reprograms acinar cells to...

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Main Authors: Yuan, Yuan, Hartland, Kate, Boskovic, Zarko, Wang, Yikai, Walpita, Deepika, Lysy, Philippe A., Zhong, Cheng, Young, Damian W., Kim, Young-kwon, Tolliday, Nicola J, Sokal, Etienne M., Schreiber, Stuart L., Wagner, Bridget K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927138/
https://ncbi.nlm.nih.gov/pubmed/24290880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.10.013
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