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Mechanism of ultraviolet-induced mutagenesis: Extent and fidelity of in vitro DNA synthesis on irradiated templates

The effect of UV irradiation on the extent and fidelity of DNA synthesis in vitro was studied by using homopolymers and primed single-stranded ϕX174 phage DNA as substrates. Unfractionated and fractionated cell-free extracts from Escherichia coli pol(+) and polA1 mutants as well as purified DNA poly...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Villani, Giuseppe, Boiteux, Serge, Radman, Miroslav
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1978
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/356043/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.7.3037
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