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In human retinoblastoma Y79 cells okadaic acid–parthenolide co-treatment induces synergistic apoptotic effects, with PTEN as a key player

Retinoblastoma is the most common intraocular malignancy of childhood. In developing countries, treatment is limited, long-term survival rates are low and current chemotherapy causes significant morbidity to pediatric patients and significantly limits dosing. Therefore there is an urgent need to ide...

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Autors principals: Di Fiore, Riccardo, Drago-Ferrante, Rosa, D’Anneo, Antonella, Augello, Giuseppa, Carlisi, Daniela, De Blasio, Anna, Giuliano, Michela, Tesoriere, Giovanni, Vento, Renza
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926889/
https://ncbi.nlm.nih.gov/pubmed/23938948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.25944
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