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Interferon α interferes with immunological tolerance

The ability of regulatory T cells (Tregs) to promote immunological tolerance represents an important obstacle in cancer immunotherapy. We have recently discovered that the clinically established immunotherapeutic agent interferon α (IFNα) inactivates the suppressive functions of human Tregs. Here, w...

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Bibliografski detalji
Glavni autori: Becker, Christian, Bopp, Tobias, Steinbrink, Kerstin
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926876/
https://ncbi.nlm.nih.gov/pubmed/24575381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27528
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