Low concentrations of indomethacin inhibit phospholipase A2 of rabbit polymorphonuclear leukocytes.
Inhibition of prostaglandin synthesis by indomethacin, a drug with anti-inflammatory properties, has been attributed to its action on fatty acid cyclooxygenase. However, prostaglandin synthesis would also be inhibited if precursor fatty acids were not supplied. We find that indomethacin inhibits pho...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1978
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392685/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/275865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.6.2955 |
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