Low concentrations of indomethacin inhibit phospholipase A2 of rabbit polymorphonuclear leukocytes.

Inhibition of prostaglandin synthesis by indomethacin, a drug with anti-inflammatory properties, has been attributed to its action on fatty acid cyclooxygenase. However, prostaglandin synthesis would also be inhibited if precursor fatty acids were not supplied. We find that indomethacin inhibits pho...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Kaplan, L, Weiss, J, Elsbach, P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1978
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392685/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/275865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.6.2955
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