A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors

Beyond their ability to inhibit cholesterol biosynthesis, the statins have pleiotropic effects that include anti-inflammatory and immunomodulatory activities. Statins could have clinical utility, alone or in combination with other chemotherapeutics, in the treatment of cancer. The mechanisms that un...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mira, Emilia, Carmona-Rodríguez, Lorena, Tardáguila, Manuel, Azcoitia, Iñigo, González-Martín, Alicia, Almonacid, Luis, Casas, Josefina, Fabriás, Gemma, Mañes, Santos
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2013
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926827/
https://ncbi.nlm.nih.gov/pubmed/24317954
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