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Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma
Although there is a relationship between DNA repair deficiency and temozolomide (TMZ) resistance in glioblastoma (GBM), it remains unclear which molecule is associated with GBM recurrence. We isolated three TMZ-resistant human GBM cell lines and examined the expression of O(6)-methylguanine-DNA meth...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Impact Journals LLC
2013
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926825/ https://ncbi.nlm.nih.gov/pubmed/24259277 |
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