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Pigmented-MDCK (P-MDCK) Cell Line with Tunable Melanin Expression: An In Vitro Model for the Outer Blood-Retinal-Barrier

PURPOSE: Retinal pigment epithelium, which forms the outer blood-retinal-barrier, is a critical barrier for transport of drugs to the retina. The purpose of this study was to develop a pigmented MDCK (P-MDCK) cell line as a rapidly established in vitro model for the outer blood-retinal-barrier to as...

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Detalhes bibliográficos
Main Authors: Kadam, Rajendra S., Scheinman, Robert. I., Kompella, Uday B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926804/
https://ncbi.nlm.nih.gov/pubmed/23003570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300305f
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