Nafcillin Enhances Innate Immune-Mediated Killing of Methicillin-Resistant Staphylococcus aureus

Based on in vitro synergy studies, the addition of nafcillin to daptomycin was used to treat refractory methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. Daptomycin is a de facto cationic antimicrobial peptide in vivo, with antistaphylococcal mechanisms reminiscent of innate host defens...

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Bibliografiska uppgifter
Huvudupphovsmän: Sakoulas, George, Okumura, Cheryl Y., Thienphrapa, Wdee, Olson, Joshua, Nonejuie, Poochit, Dam, Quang, Dhand, Abhay, Pogliano, Joseph, Yeaman, Michael R., Hensler, Mary E., Bayer, Arnold S., Nizet, Victor
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926703/
https://ncbi.nlm.nih.gov/pubmed/24297496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-013-1100-7
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