PDGF-induced PI3K-mediated signaling enhances the TGF-β-induced osteogenic differentiation of human mesenchymal stem cells in a TGF-β-activated MEK-dependent manner

Transforming growth factor-β (TGF-β) is a critical regulator of osteogenic differentiation and the platelet-derived growth factor (PDGF) is a chemoattractant or mitogen of osteogenic mesenchymal cells. However, the combined effects of these regulators on the osteogenic differentiation of mesenchymal...

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Main Authors: YOKOTA, JUN, CHOSA, NAOYUKI, SAWADA, SHUNSUKE, OKUBO, NAOTO, TAKAHASHI, NORIKO, HASEGAWA, TOMOKAZU, KONDO, HISATOMO, ISHISAKI, AKIRA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926498/
https://ncbi.nlm.nih.gov/pubmed/24378341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2013.1606
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