Effect of vildagliptin, a dipeptidyl peptidase 4 inhibitor, on cardiac hypertrophy induced by chronic beta-adrenergic stimulation in rats

BACKGROUND: Heart failure with left ventricular (LV) hypertrophy is often associated with insulin resistance and inflammation. Recent studies have shown that dipeptidyl peptidase 4 (DPP4) inhibitors improve glucose metabolism and inflammatory status. We therefore evaluated whether vildagliptin, a DP...

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Autori principali: Miyoshi, Toru, Nakamura, Kazufumi, Yoshida, Masashi, Miura, Daiji, Oe, Hiroki, Akagi, Satoshi, Sugiyama, Hiroki, Akazawa, Kaoru, Yonezawa, Tomoko, Wada, Jun, Ito, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926272/
https://ncbi.nlm.nih.gov/pubmed/24521405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-43
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