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Protection of palmitic acid-mediated lipotoxicity by arachidonic acid via channeling of palmitic acid into triglycerides in C2C12
BACKGROUND: Excessive saturated fatty acids have been considered to be one of major contributing factors for the dysfunction of skeletal muscle cells as well as pancreatic beta cells, leading to the pathogenesis of type 2 diabetes. RESULTS: PA induced cell death in a dose dependent manner up to 1.5 ...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926261/ https://ncbi.nlm.nih.gov/pubmed/24521082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-21-13 |
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