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Combinational delivery of c-Myc siRNA and nucleoside analogues in a single, synthetic nanocarrier for targeted cancer therapy

The treatment of aggressive non-small-cell lung cancer (NSCLC) depends on the creation of new therapeutic regimens in clinical settings. In this study, we developed a Lipid/Calcium/Phosphate (LCP) nanoparticle that combines chemotherapy with gene therapy. By encapsulating a chemodrug, gemcitabine mo...

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Detalhes bibliográficos
Main Authors: Zhang, Yuan, Peng, Lei, Mumper, Russell J, Huang, Leaf
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926217/
https://ncbi.nlm.nih.gov/pubmed/23932296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.07.050
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