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Microtubule-dependent regulation of mitotic protein degradation
Accurate cell division depends on tightly regulated ubiquitylation events catalyzed by the anaphase-promoting complex. Among its many substrates, the APC/C triggers the degradation of proteins that stabilize the mitotic spindle, and loss or accumulation of such spindle assembly factors can result in...
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Main Authors: | , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926196/ https://ncbi.nlm.nih.gov/pubmed/24462202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.12.022 |
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