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Microtubule-dependent regulation of mitotic protein degradation

Accurate cell division depends on tightly regulated ubiquitylation events catalyzed by the anaphase-promoting complex. Among its many substrates, the APC/C triggers the degradation of proteins that stabilize the mitotic spindle, and loss or accumulation of such spindle assembly factors can result in...

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Detalhes bibliográficos
Main Authors: Song, Ling, Craney, Allison, Rape, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926196/
https://ncbi.nlm.nih.gov/pubmed/24462202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.12.022
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