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Conformationally restricted bicyclic analogs of somatostatin.

A model for a biologically active conformation of somatostatin is proposed. This model is based primarily on the biological results obtained with novel bicyclic somatostatin analogs having a covalent bridge replacing the side chains of residues 5 and 10, 6 and 11, and 5 and 12, respectively, rather...

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Detalhes bibliográficos
Main Authors: Veber, D F, Holly, F W, Paleveda, W J, Nutt, R F, Bergstrand, S J, Torchiana, M, Glitzer, M S, Saperstein, R, Hirschmann, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC392617/
https://ncbi.nlm.nih.gov/pubmed/208068
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