Alveolar epithelial cells in idiopathic pulmonary fibrosis display upregulation of TRAIL, DR4 and DR5 expression with simultaneous preferential over-expression of pro-apoptotic marker p53

Idiopathic pulmonary fibrosis (IPF) is a progressive, debilitating, and fatal lung disease of unknown aetiology with no current cure. The pathogenesis of IPF remains unclear but repeated alveolar epithelial cell (AEC) injuries and subsequent apoptosis are believed to be among the initiating/ongoing...

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Bibliografske podrobnosti
Main Authors: Akram, Khondoker M, Lomas, Nicola J, Forsyth, Nicholas R, Spiteri, Monica A
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2014
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925899/
https://ncbi.nlm.nih.gov/pubmed/24551275
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